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An increase in the number of mumps cases in the Czech Republic, 2005-2006
N Boxall1, M Kubinyiova, V Príkazský
1National Institute of Public Health, Prague, Czech Republic.
Abstract:
The Czech Republic has had a two-dose measles, mumps and rubella (MMR) vaccination programme since 1987. The last outbreak of mumps was reported in 2002, but an increase in the number of mumps cases was observed in 2005, starting in October that year. We analysed routinely collected surveillance data from 1 January 2005 to 30 June 2006 to show the magnitude of the increase and describe the most affected groups in order to better target prevention and control strategies. In the 18-month period examined, 5,998 cases of mumps were notified, with a peak incidence in May 2006. No deaths were recorded, but 21% of cases were hospitalised. Incidence was lowest in the Plzen region (1.9/100,000) and highest in Zlin (118.6/100,000). There were more male (61.8%) than female cases. The age of the cases ranged from 0 to 80 years. The highest incidence rate was observed in the age group of 15 to 19 years, in which 87% of cases had received two doses of mumps vaccine. The average age of unvaccinated cases was 22.9 years, while for cases vaccinated with two doses it was 14.5 years. Although vaccine effectiveness could not be calculated from the data available, possible reasons for highly-vaccinated cases occurring are discussed.
Insights
An increase in mumps cases occurred in the Czech Republic from 2005-2006, primarily affecting adolescents. Many cases were in individuals who had received two doses of the measles, mumps, and rubella (MMR) vaccine.
Area of Science:
- Epidemiology
- Public Health
- Vaccinology
Background:
- The Czech Republic has maintained a two-dose measles, mumps, and rubella (MMR) vaccination program since 1987.
- A notable increase in mumps cases was observed starting in October 2005, following the last reported outbreak in 2002.
Purpose of the Study:
- To analyze the magnitude of the mumps increase between January 2005 and June 2006.
- To identify the most affected demographic groups to inform prevention and control strategies.
Main Methods:
- Utilized routinely collected surveillance data from January 2005 to June 2006.
- Analyzed case numbers, incidence rates by region and age, and vaccination status.
Main Results:
- 5,998 mumps cases were reported, peaking in May 2006.
- Highest incidence was in the Zlin region (118.6/100,000) and the 15-19 year age group.
- 87% of cases in the highest incidence group had received two MMR vaccine doses; average age of vaccinated cases was 14.5 years.
Conclusions:
- The study highlights a significant mumps resurgence in the Czech Republic.
- The high proportion of vaccinated individuals among cases warrants further investigation into vaccine effectiveness and potential contributing factors.
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