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Intravenous immunoglobulins in the treatment of immune neuropathies
Bernd C Kieseier1, Gerd Meyer Zu Hörste, Helmar C Lehmann
1Department of Neurology, Heinrich-Heine-University, Duesseldorf, Germany. bernd.kieseier@uni-duesseldorf.de
Purpose Of Review:
The aim of this review is to describe the value of high-dose polyclonal intravenous immunoglobulins as a treatment option in autoimmune disorders affecting the peripheral nervous system.
Recent Findings:
A randomized placebo-controlled trial in patients with chronic inflammatory demyelinating polyradiculoneuropathy revealed short-term and long-term efficacy and safety of intravenous immunoglobulins as a treatment option for the chronically inflamed peripheral nervous system. Case reports suggest that the subcutaneous administration of immunoglobulins may represent a convenient alternative.
Summary:
Intravenous immunoglobulin represents an effective and safe treatment option in patients with autoimmune-mediated diseases affecting the peripheral nerves.
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