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Related Concept Videos

Micelles01:30

Micelles

Micelle formation is an intricate process that hinges on the properties of amphiphilic or amphipathic molecules and the conditions of the system in which they are found. Amphiphilic molecules, which have both hydrophilic (water-attracting) and hydrophobic (water-repelling) parts, play a critical role in this process.In aqueous environments, these molecules arrange themselves such that their hydrophilic heads are turned towards the water phase, while their hydrophobic tails are oriented away...

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Related Experiment Video

Updated: Jul 2, 2026

A Tripeptide-Stabilized Nanoemulsion of Oleic Acid
10:42

A Tripeptide-Stabilized Nanoemulsion of Oleic Acid

Published on: February 27, 2019

Nanoscale double emulsions stabilized by single-component block copolypeptides.

Jarrod A Hanson1, Connie B Chang, Sara M Graves

  • 1Bioengineering Department, University of California, Los Angeles, California 90095, USA.

Nature
|September 5, 2008
PubMed
Summary

Researchers developed a simple method for creating stable double nanoemulsions using synthetic copolypeptide surfactants. This breakthrough enables mass production of robust nanoemulsions for advanced encapsulation in food, cosmetics, and drug delivery.

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Last Updated: Jul 2, 2026

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Published on: February 27, 2019

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10:53

Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions

Published on: October 10, 2016

Area of Science:

  • Colloid and Surface Science
  • Materials Science
  • Biotechnology

Background:

  • Double emulsions (water-in-oil-in-water) offer unique encapsulation benefits due to their compartmentalized structure.
  • Existing methods struggle to produce stable double nanoemulsions (droplets < 100 nm).
  • Applications in food, cosmetics, and drug delivery require robust and controllable encapsulation systems.

Purpose of the Study:

  • To develop a method for producing stable double nanoemulsions.
  • To investigate the efficacy of single-component synthetic amphiphilic diblock copolypeptide surfactants for stabilization.
  • To demonstrate the potential for mass production and diverse applications.

Main Methods:

  • Utilized a simple preparation process for water-in-oil-in-water double emulsions.
  • Employed single-component, synthetic amphiphilic diblock copolypeptide surfactants for stabilization.
  • Tested droplet stability under extreme flow conditions.

Main Results:

  • Successfully prepared and stabilized robust double nanoemulsions for extended periods (months).
  • Demonstrated that the synthetic surfactants effectively stabilize droplets even under extreme flow.
  • Achieved mass production of stable double nanoemulsions.

Conclusions:

  • Synthetic amphiphilic diblock copolypeptides are effective single-component stabilizers for double nanoemulsions.
  • The developed process allows for simple, scalable production of robust double nanoemulsions.
  • These nanoemulsions are highly suitable for nanostructured encapsulation in various industries, including food, cosmetics, and drug delivery.