Documenting adherence to psychostimulants in children with ADHD
Alice Charach1, Amy Gajaria, Anna Skyba
1Research Institute, The Hospital for Sick Children, Toronto, ON. alice.charach@sickkids.ca
Summary
The Stimulant Adherence Measure accurately assesses stimulant medication adherence in children with ADHD over three months. This telephone interview is a valid and reliable tool for tracking medication use in pediatric ADHD treatment.
Area of Science:
- Pediatric Psychology
- Pharmacological Treatment Adherence
- Child Psychiatry
Background:
- Accurate measurement of medication adherence is crucial for effective treatment of Attention-Deficit/Hyperactivity Disorder (ADHD).
- Existing methods for assessing adherence may have limitations in real-world clinical settings.
- The Stimulant Adherence Measure (SAM) was developed as a semi-structured telephone interview to assess adherence to stimulant medication.
Purpose of the Study:
- To evaluate the validity of the Stimulant Adherence Measure (SAM) by comparing it with objective data from the Medication Event Monitoring System (MEMS).
- To assess the inter-rater reliability of the SAM.
- To determine the stability of the SAM's measurements over a 3-month period.
Main Methods:
- A study involving 22 children (mean age 11.85 years) diagnosed with ADHD and treated with psychostimulants.
- Participants used a MEMS device to record stimulant medication intake.
- Children and parents completed the SAM via telephone interview for three consecutive months, reporting medication use for the past 7 and 28 days.
Main Results:
- Good to excellent agreement was found between MEMS data and parent reports for both 7-day and 28-day recall periods across all three months (ICC values ranging from 0.663 to 0.907).
- Good agreement was observed between MEMS and child reports for the 7-day recall period (ICC values ranging from 0.542 to 0.773).
- Excellent inter-rater reliability was demonstrated for the SAM (ICC=0.956), with no significant interview order effect.
Conclusions:
- The Stimulant Adherence Measure (SAM) is a valid and reliable tool for assessing stimulant medication adherence in children with ADHD.
- The SAM's stability over three months and its good inter-rater reliability support its use in clinical practice.
- This telephone-based assessment offers a practical method for monitoring medication adherence in pediatric ADHD management.
Keywords:
attention deficit disorder with hyperactivitycentral nervous system stimulantspatient compliancereproducibility of resultstreatment refusalMore Related Videos
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