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Detection of the pH-dependent Activity of Escherichia coli Chaperone HdeB In Vitro and In Vivo
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Effects of pH on the activity and structure of choline oxidase from Alcaligenes species

Azadeh Hekmat1, Ali Akbar Saboury, Ali Akbar Moosavi-Movahedi

  • 1Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran.

Acta Biochimica Polonica
|September 5, 2008
PubMed

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Indirect-Acting Cholinergic Agonists: Mechanism of Action

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Indirect-Acting Cholinergic Agonists: Chemistry and Structure-Activity Relationship

Indirect-acting cholinergic agonists are agents that interact with the acetylcholinesterase enzyme in the synaptic cleft, preventing the breakdown of acetylcholine into choline and acetate. Consequently, the concentration of acetylcholine in the synaptic cleft increases. These agonists can be classified into reversible and irreversible inhibitors based on their duration of action.
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