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Updated: Jul 2, 2026
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Enhanced Reduced Representation Bisulfite Sequencing for Assessment of DNA Methylation at Base Pair Resolution
Published on: February 24, 2015
Reduced-representation methylation mapping
Jeffrey A Jeddeloh1, John M Greally, Oliver J Rando
1Roche NimbleGen Inc, Research and Development, 500 S. Rosa Rd, Madison, WI 53719, USA. jeffrey.jeddeloh@roche.com
Genome Biology
|September 6, 2008
Abstract:
The power of massively parallel sequencing has been harnessed to map cytosine methylation patterns in the mouse genome, allowing insights into the relationship of methylation with DNA sequence, histone modifications, transcriptional activity and dynamic changes in methylation status during differentiation.
