Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Photoreceptors and Visual Pathways

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The impact of climate and demographic changes on future mortality in Brussels, Belgium.

Public health·2024

Same author

[CORNEAL BURN: CLINICAL PROFILE, CONTRIBUTION OF ANTERIOR SEGMENT OPTICAL COHERENCE TOMOGRAPHY AND MANAGEMENT - EIGHT CASES].

Annals of burns and fire disasters·2024

Same author

Tuberculous subretinal abscess: Case report.

Journal francais d'ophtalmologie·2024

Same author

[Trichilemmal cyst of the eyelid: Clinical and histological features].

Journal francais d'ophtalmologie·2023

Same author

[Ophthalmologic involvement in glycogen storage disease type 1: Case report].

Journal francais d'ophtalmologie·2023

Same author

Bilateral premacular hemorrhage secondary to Hodgkin's lymphoma: Case report.

Journal francais d'ophtalmologie·2023

Search research articles

Related Experiment Video

Updated: Jul 2, 2026

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

Published on: July 24, 2020

[Ocular ochronosis. A case report].

N Ben Rayana¹, N Chahed, S Khochtali

¹Service d'Ophtalmologie, Centre Hospitalo-Universitaire Farhat Hached, Sousse, Tunisie. narjesbenrayana@yahoo.fr

Journal Francais D'Ophtalmologie

|September 6, 2008

Summary

This summary is machine-generated.

Ochronosis, a rare inherited disease, involves pigment deposition in tissues, causing joint issues. This case highlights conjunctival pigment in a patient with ochronosis and back pain.

Related Experiment Videos

Last Updated: Jul 2, 2026

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

Published on: July 24, 2020

Area of Science:

Biochemistry
Genetics
Ophthalmology

Background:

Ochronosis, also known as alkaptonuria, is a rare inherited metabolic disorder.
Characterized by the accumulation of homogentisic acid, leading to pigment deposition in connective tissues.

Observation:

A 47-year-old patient presented with lower back pain.
Ophthalmologic examination revealed dark pigment deposits in the conjunctiva.

Findings:

The patient's diagnosis of ochronosis was confirmed by elevated urinary homogentisic acid levels.
Clinical manifestations included arthropathy and visible conjunctival pigmentation.

Implications:

This case underscores the importance of ophthalmologic examination in diagnosing ochronosis.
Early detection and management of ochronosis can help mitigate complications like arthropathy.