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[Follow up of asthmatic children: definition and measurement tools]

J de Blic1, A Deschildre,

  • 1Service de Pneumologie et allergologie pédiatriques, Hôpital Necker Enfants Malades, Paris, France. j.deblic@nck.aphp.fr

Revue Des Maladies Respiratoires
|September 6, 2008
PubMed

Insights

Asthma management guidelines stress monitoring disease activity over weeks using clinical and functional tools. Measuring expired nitric oxide (NO) shows promise for improving routine paraclinical assessments in asthma care.

Area of Science:

  • Pulmonology
  • Allergy and Immunology
  • Pediatric Respiratory Medicine

Background:

  • Current asthma management guidelines emphasize monitoring disease activity over several weeks.
  • This monitoring principle applies across all asthma severity levels.
  • Clinical and functional assessments are the primary tools for asthma monitoring.

Purpose of the Study:

  • To review the established clinical and functional monitoring tools for asthma management.
  • To highlight the role of expired nitric oxide (NO) as a non-invasive marker of airway inflammation.
  • To explore the potential of expired NO measurement in enhancing routine paraclinical assessments.

Main Methods:

  • Systematic evaluation of clinical parameters including symptoms, exercise discomfort, and beta-2 agonist use.
  • Utilizing validated questionnaires such as ATAQ and ACT for symptom assessment.
  • Performing regular respiratory function assessments for pediatric asthma patients.
  • Investigating the measurement of expired nitric oxide (NO) as a non-invasive inflammatory marker.

Main Results:

  • Clinical parameters like daytime/nocturnal symptoms and beta-2 agonist use are crucial at consultations and exacerbations.
  • Respiratory function assessment frequency should align with the therapeutic management program.
  • Expired nitric oxide (NO) measurement is the most established non-invasive method for assessing airway inflammation.
  • Expired NO has the potential to enhance current paraclinical monitoring in asthma.

Conclusions:

  • Effective asthma management relies on consistent monitoring of disease activity using clinical and functional indicators.
  • Expired nitric oxide (NO) measurement represents a valuable addition to the non-invasive assessment of airway inflammation.
  • Integrating expired NO monitoring may improve the comprehensiveness of routine paraclinical evaluations in asthma care.

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