Related Experiment Video
Updated: Jul 2, 2026

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery
Published on: April 14, 2016
[Pain and its treatment reflected in time].
M A Rauschmann1, K-D Thomann, F Geiger
1Abteilung für Wirbelsäulenerkrankungen, Orthopädische Universitätsklinik Friedrichsheim gGmbH, Marienburgstrasse 2, 60528, Frankfurt am Main, Deutschland. m.rauschmann@friedrichsheim.de
The evolution of pain therapy and anesthesiology in surgery is traced, highlighting key drug developments like nitrous oxide and morphine. Modern pain management integrates these advances with physiology and psychology for individualized patient care.
Area of Science:
- Medical History
- Anesthesiology
- Pain Management
Context:
- The historical development of surgical pain therapy and anesthesiology is intrinsically linked to pharmacological advancements.
- Key milestones include the introduction of nitrous oxide, ether, morphine, and early local anesthetics.
- Understanding pain physiology and psychological factors has been crucial for progress.
Purpose:
- To chronicle the historical trajectory of pain therapy and anesthesiology within surgery.
- To discuss the impact of specific drug discoveries on pain management.
- To illustrate the foundation of modern perioperative pain concepts.
Summary:
- This article details the history of pain therapy and anesthesiology in surgery, emphasizing the critical role of medication development.
- It covers the introduction of significant substances like nitrous oxide, ether, morphine, and local anesthetics.
- These advancements, coupled with insights into pain physiology and psychology, have shaped contemporary perioperative pain management strategies.
Impact:
- The historical progression has led to modern multimodal pain therapy, optimizing individualized patient treatment plans.
- This evolution underscores the interdisciplinary nature of current pain management, involving various specialties.
- The focus is on tailoring treatments for acute, perioperative, and chronic pain conditions.
Related Concept Videos
Analgesia and Pain Management
Pain
Nociception
Blood and Nerve Supply to the Bones
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
Methods of Documentation II: POMR
Guidelines for Nursing Documentation II
Timely documentation is crucial to ensure continuity of care for patients. Any delays in recording or reporting medical information can result in medical errors and even adverse patient outcomes. From medication administration to diagnostic test results, every detail must be accurately and promptly documented to provide the best possible care for patients.

