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Controlled axial coordination: solid-phase synthesis and purification of metallo-radiopharmaceuticals

Helen M Betts1, Peter J Barnard, Simon R Bayly

  • 1Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK.

Angewandte Chemie (International Ed. in English)
|September 6, 2008
PubMed
Abstract

No abstract available in PubMed .

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Stereoisomerism02:52

Stereoisomerism

Isomerism in Complexes
Isomers are different chemical species that have the same chemical formula.
Transition metal complexes often exist as geometric isomers, in which the same atoms are connected through the same types of bonds but with differences in their orientation in space. Coordination complexes with two different ligands in the cis and trans positions from a ligand of interest form isomers. For example, the octahedral [Co(NH3)4Cl2]+ ion has two isomers (Figure 1) In the cis...

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