Related Experiment Video
Updated: Jul 2, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
[Obesity paradox in patients with coronary artery disease or heart failure]
Stefano De Servi1, Giuseppe Mariani, Aldo Pietro Maggioni
1Dipartimento Cardiovascolare, AO Ospedale Civile, Legnano.
Abstract:
Several studies have shown an inverse relationship between obesity and mortality of patients who survived an acute myocardial infarction or a revascularization procedure, the so-called "obesity paradox". These findings should be considered very cautiously due to several confounding factors, not adequately taken into account by the adjustment models. Similar evidences and considerations have been drawn by studies conducted in patients with acute or chronic heart failure. In these clinical conditions, prospective studies to assess the role of intentional weight loss should be specifically designed.
Related Concept Videos
Drug Dosing: Obese Patients
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion
Heart Failure VI: Adjunct Therapies
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution
Pathophysiology of Heart Failure
Heart Failure II: Pathophysiology