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Updated: Jul 2, 2026

Setting Up a Stroke Team Algorithm and Conducting Simulation-based Training in the Emergency Department - A Practical Guide
09:52

Setting Up a Stroke Team Algorithm and Conducting Simulation-based Training in the Emergency Department - A Practical Guide

Published on: January 15, 2017

The approach to optimizing stroke care.

Peter D Panagos1

  • 1Department of Emergency Medicine, The Warren Alpert School of Medicine of Brown University, Providence, RI 02903, USA. ppanagos@lifespan.org

The American Journal of Emergency Medicine
|September 9, 2008
PubMed
Summary
This summary is machine-generated.

Stroke treatment requires prompt action, focusing on thrombolysis and supportive care. For ischemic stroke, antithrombotic therapy with agents like clopidogrel or aspirin plus extended-release dipyridamole is crucial for preventing secondary strokes.

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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

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Last Updated: Jul 2, 2026

Setting Up a Stroke Team Algorithm and Conducting Simulation-based Training in the Emergency Department - A Practical Guide
09:52

Setting Up a Stroke Team Algorithm and Conducting Simulation-based Training in the Emergency Department - A Practical Guide

Published on: January 15, 2017

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

Area of Science:

  • Neurology
  • Emergency Medicine
  • Cardiovascular Medicine

Background:

  • Stroke is a primary cause of mortality, long-term disability, and dependency.
  • Effective acute stroke management necessitates a coordinated approach involving thrombolysis and comprehensive supportive care.
  • Subacute ischemic stroke treatment emphasizes initiating antithrombotic therapy and mitigating secondary stroke risk through risk factor management.

Purpose of the Study:

  • To highlight the critical role of emergency medicine physicians in acute stroke management.
  • To outline optimal antithrombotic strategies for ischemic stroke patients, particularly those ineligible for thrombolysis.
  • To emphasize the importance of risk factor modification in preventing recurrent strokes.

Main Methods:

  • Review of current treatment guidelines and evidence for acute and subacute stroke management.
  • Analysis of the role of emergency physicians in initiating thrombolysis and antiplatelet therapy.
  • Evaluation of the efficacy of different antithrombotic agents, including aspirin, clopidogrel, and aspirin/extended-release dipyridamole (ER-DP).

Main Results:

  • Most emergency department stroke patients require antithrombotic therapy due to narrow thrombolysis timeframes.
  • Aspirin, clopidogrel, and aspirin plus ER-DP are effective in reducing recurrent stroke risk.
  • Guidelines recommend clopidogrel or aspirin plus ER-DP over aspirin monotherapy, especially for aspirin-allergic patients.

Conclusions:

  • Emergency medicine physicians play a vital role in stroke care, from initiating thrombolysis to prescribing secondary stroke prevention therapies.
  • Antithrombotic therapy is essential for preventing secondary strokes in the majority of ischemic stroke patients.
  • Understanding and utilizing appropriate antiplatelet agents like clopidogrel and aspirin plus ER-DP is critical for improving patient outcomes.