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Updated: Jul 2, 2026
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Chromosome Screening of Human Preimplantation Embryos by Using Spent Culture Medium: Sample Collection and Chromosomal Ploidy Analysis
Published on: September 7, 2021
The effect of blastomere biopsy on preimplantation mouse embryo development and global gene expression
Francesca E Duncan1, Paula Stein, Carmen J Williams
1Center for Research on Reproduction and Women's Health, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Fertility and Sterility
|September 9, 2008
Abstract:
The blastomere biopsy procedure does not affect preimplantation embryo development or global patterns of gene expression in a mouse model of Preimplantation Genetic Testing (PGT). However, zona breaching, which is inherent to the blastomere biopsy procedure, causes significant premature and sometimes abnormal hatching.
