Related Experiment Video
Updated: Jul 2, 2026

Isolation, Characterization, and Total DNA Extraction to Identify Endophytic Fungi in Mycoheterotrophic Plants
Published on: May 5, 2023
11-Hydroxymonocerin from the plant endophytic fungus Exserohilum rostratum
Ruengrit Sappapan1, Damrong Sommit, Nattaya Ngamrojanavanich
1Program in Biotechnology, Chulalongkorn University, Bangkok 10330 Thailand.
Abstract:
A new analogue of monocerin, 11-hydroxymonocerin (2), along with monocerin (1) and 12-hydroxymonocerin (3) were isolated from cultures of Exserohilum rostratum, a fungal strain endophytic in Stemona sp. The structure of 2 was determined by analysis of NMR and MS data and by comparison of spectroscopic data to those of 1. Monocerin (1) and 11-hydroxymonocerin (2) displayed activity against Plasmodium falciparum (K1, multidrug-resistant strain) with IC50 values of 0.68 and 7.70 microM, respectively. None of the compounds were cytotoxic against any of the tumor cell lines tested.
Related Concept Videos
Antifungal Agents
Microbe-Plant Interactions

