Chest pain in the emergency department: incidence, clinical characteristics and risk stratification
Manuel Martínez-Sellés1, Héctor Bueno, Alberto Sacristán
1Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, Madrid, Spain. mmselles@secardiologia.es
Insights
A simple CPU-65 index can identify patients with chest pain at very low risk. Half of emergency department patients with chest pain had a score of 0, indicating no acute myocardial infarction or death during admission.
Area of Science:
- Emergency Medicine
- Cardiology
- Clinical Risk Stratification
Background:
- Chest pain is a frequent emergency department complaint with variable management.
- Risk stratification is crucial for efficient chest pain evaluation.
Purpose of the Study:
- To characterize emergency department patients presenting with nontraumatic chest pain.
- To assess the utility of the CPU-65 index for risk stratification in these patients.
Main Methods:
- Prospective registry of 1518 patients with nontraumatic chest pain.
- Data collection included patient demographics, pain characteristics, and diagnostic tests.
- The CPU-65 index (Comorbid diabetes, typical Pain, Use of aspirin, age ≥65 years) was calculated.
Main Results:
- 909 patients (59.9%) had nonischemic chest pain, 239 (15.7%) had ischemic pain.
- Acute myocardial infarction (AMI) occurred in 6.5% of patients; 0.5% died during admission.
- A CPU-65 index score of 0 was observed in 50% of patients, with no associated AMI or mortality.
Conclusions:
- The CPU-65 index effectively identifies a significant proportion of chest pain patients at very low risk.
- This index can aid in streamlining emergency department workflows for chest pain evaluation.
Introduction And Objectives:
Although chest pain is a common presenting symptom in emergency departments, its clinical management is highly variable. Our aims were to describe the characteristics of patients with chest pain and to evaluate the usefulness of the CPU-65 index for risk stratification. The CPU-65 index awards one point for each of the following variables: Comorbid diabetes, typical Pain, Use of aspirin, and age 65 years or more.
Methods:
Details of emergency department patients admitted for nontraumatic chest pain were recorded in a prospective registry.
Results:
Over a 3-month period, 1518 patients were admitted with nontraumatic chest pain (6.1% of medical emergencies). Chest pain was classified as nonischemic in 909 patients (59.9%), undefined in 370 (24.4%) and ischemic in 239 (15.7%). An ECG was performed in 1342 patients (88.4%), the troponin-T level was measured in 656 (43.2%), chest radiography was performed in 831 (54.7%), and 385 (25.4%) were evaluated by the cardiologist on duty. Overall, 230 (15.2%) were admitted to hospital; of these, 99 (6.5%) had an acute myocardial infarction (AMI) and seven (0.5%) died during admission. Among patients discharged from the emergency department, the most frequent diagnoses were atypical chest pain (59%) and respiratory infection (12%). The CPU-65 index was associated with the presence of AMI. In total, 50% of patients had a CPU-65 index score of 0, none of whom either had an AMI or died during admission.
Conclusions:
Half of all patients who presented at an emergency department with chest pain were at a very low risk.
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