Ca2+-activated Cl- current in retinal arteriolar smooth muscle

Mary K McGahon1, Maurice A Needham, C Norman Scholfield

  • 1Centre for Vision and Vascular Sciences, School of Medicine and Dentistry, The Queen's University of Belfast, Institute of Clinical Sciences, The Royal Victoria Hospital, United Kingdom.

Summary

This study characterizes the calcium-activated chloride current (I(Cl(Ca))) in retinal artery cells. This current, activated by calcium influx or release, contributes to vasoconstriction induced by certain agonists.

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