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Updated: Jul 1, 2026

New Methods to Study Gustatory Coding
Published on: June 29, 2017
ERK-dependent PSD-95 induction in the gustatory cortex is necessary for taste learning, but not retrieval
Alina Elkobi1, Ingrid Ehrlich, Katya Belelovsky
1Center for Brain and Behavior, Department of Neurobiology and Ethology, University of Haifa, Haifa 30905, Israel.
Abstract:
The processes underlying long-term memory formation in the neocortex are poorly understood. Using taste learning, we found learning-related induction of PSD-95 in the gustatory cortex, which was temporally restricted, coupled to the learning of a novel, but not familiar, taste and controlled by ERK. Using temporally and spatially restricted RNA interference knockdown of PSD-95 in vivo, we found that PSD-95 induction is necessary for learning novel tastes, but not for the recollection of familiar ones.
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