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Hypnozoites of Plasmodium simiovale
F B Cogswell1, W E Collins, W A Krotoski
1Tulane Regional Primate Research Center, Covington, Louisiana.
The American Journal of Tropical Medicine and Hygiene
|August 11, 1991
Abstract:
Hypnozoites of Plasmodium simiovale were detected in liver biopsies from a rhesus monkey (Macaca mulatta) inoculated eight days previously with sporozoites from heavily infected anopheline mosquitoes. The tissue forms, 6 mu in diameter, were found within the cytoplasm of hepatic parenchymal cells by immunofluorescence and restained with Giemsa. This is the first report of latent, pre-erythrocytic stages from an ovale-type relapsing malaria.