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Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae
Published on: February 24, 2023
Avian mycoplasma and pathogenicity--a review
1Sub-Department of Avian Medicine, University of Liverpool Veterinary Field Station, Neston, Wirral, U.K.
Abstract:
M. gallisepticum, M. synoviae and M. meleagridis are pathogenic strains of avian mycoplasma. M. gallisepticum and M. synoviae affect the chicken and turkey while M. meleagridis is associated with disease in the turkey. The tissues affected and the lesions are described and the influence on disease production of certain factors is considered. They include the age of the host, route of infection, numbers and virulence of organisms and predisposing and debilitating factors. The mechanism of pathogenesis is also indicated and reference made to a method of determining virulence.
Insights
Avian mycoplasma strains Mycoplasma gallisepticum, Mycoplasma synoviae, and Mycoplasma meleagridis cause disease in poultry. Factors influencing disease severity and pathogenesis mechanisms are discussed.
Area of Science:
- Veterinary Microbiology
- Avian Pathology
Background:
- Mycoplasma gallisepticum, Mycoplasma synoviae, and Mycoplasma meleagridis are significant avian pathogens.
- These mycoplasmas cause respiratory and systemic diseases in chickens and turkeys.
Purpose of the Study:
- To describe the affected tissues and lesions caused by these avian mycoplasma strains.
- To analyze factors influencing disease production, including host age and infection route.
- To discuss the pathogenesis mechanisms and virulence determination methods.
Main Methods:
- Descriptive analysis of affected tissues and observed lesions.
- Consideration of host-related factors (age, immune status) and pathogen-related factors (virulence, inoculum size).
- Review of established and potential methods for virulence assessment.
Main Results:
- Specific tissues and lesions associated with M. gallisepticum, M. synoviae, and M. meleagridis infections detailed.
- Identified key factors influencing disease severity and outcome.
- Pathogenesis mechanisms outlined, with a focus on virulence factors.
Conclusions:
- Understanding the pathogenesis of these avian mycoplasmas is crucial for disease control.
- Virulence determination methods are essential for risk assessment and management strategies.
- Integrated approaches considering host and pathogen factors are needed for effective avian mycoplasma management.
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