Observations on some changes during acute S. gallinarum infection in chicks

Haematological, serological, morbid anatomical and bacteriological observations were made daily for the 9 consecutive days that followed oral infection of chicks aged 15 days with Salmonella gallinarum. The pathological changes among chicks fed with a nutritionally adequate diet containing only fish meal as the protein supplement were similar to, but in some respects more marked than, those in chicks fed with a corresponding meat-meal diet. The gradual development of a microcytic anaemia in all the infected animals probably indicated an alteration in iron absorption or metabolism in the acute stages of the infection.