Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

What is Genetic Engineering?00:49

What is Genetic Engineering?

Overview
Recombinant DNA01:09

Recombinant DNA

Overview
Gene-Environment Interactions01:20

Gene-Environment Interactions

Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...
Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One major factor that impacts genome size is whether the organism is prokaryotic or eukaryotic. In prokaryotes, the genome contains little to no non-coding sequence, such that genes are tightly clustered in groups or operons sequentially along the chromosome. Conversely, the genes in eukaryotes are punctuated by long stretches of non-coding sequence.
Genetic Screens02:46

Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...
Gene Therapy00:59

Gene Therapy

Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be inserted. The...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

West Nile virus in horses - What do you need to know to diagnose the disease?

The Canadian veterinary journal = La revue veterinaire canadienne·2018
Same author

Contact lens care tips for patients: an optometrist's perspective.

Clinical optometry·2018
Same author

Making the Most From the Money.

The Health service journal·2018
Same author

Dispatches From the Frontline.

The Health service journal·2018
Same author

How to get the message out there.

The Health service journal·2018
Same author

Thanks for sharing.

The Health service journal·2018
Same journal

Young onset dementia: enhancing the diagnostic process and post-diagnosis support.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2026
Same journal

Effect of artificial intelligence on nursing documentation and patient safety.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2026
Same journal

Strategies for responding to anger from patients, relatives and carers.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2026
Same journal

Nurses' role in detecting early and subtle signs of patient deterioration in acute hospitals.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2026
Same journal

Pulse oximetry: exploring its role, limitations and challenges in clinical practice.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2026
Same journal

Anorexia nervosa: identification and management by non-specialist nurses.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2026
See all related articles

Related Experiment Video

Updated: Jul 1, 2026

An Ecdysone Receptor-based Singular Gene Switch for Deliberate Expression of Transgene with Robustness, Reversibility, and Negligible Leakiness
06:21

An Ecdysone Receptor-based Singular Gene Switch for Deliberate Expression of Transgene with Robustness, Reversibility, and Negligible Leakiness

Published on: May 7, 2018

Gene genie.

Alison Moore

    Nursing Standard (Royal College of Nursing (Great Britain) : 1987)
    |September 10, 2008
    PubMed
    Summary
    This summary is machine-generated.

    The Human Genome Project mapped our genetic code, advancing our understanding of gene-disease links. This foundational research is key to future medical breakthroughs.

    More Related Videos

    Optogenetic Random Mutagenesis Using Histone-miniSOG in C. elegans
    04:51

    Optogenetic Random Mutagenesis Using Histone-miniSOG in C. elegans

    Published on: November 14, 2016

    Gene Trapping Using Gal4 in Zebrafish
    13:34

    Gene Trapping Using Gal4 in Zebrafish

    Published on: September 29, 2013

    Related Experiment Videos

    Last Updated: Jul 1, 2026

    An Ecdysone Receptor-based Singular Gene Switch for Deliberate Expression of Transgene with Robustness, Reversibility, and Negligible Leakiness
    06:21

    An Ecdysone Receptor-based Singular Gene Switch for Deliberate Expression of Transgene with Robustness, Reversibility, and Negligible Leakiness

    Published on: May 7, 2018

    Optogenetic Random Mutagenesis Using Histone-miniSOG in C. elegans
    04:51

    Optogenetic Random Mutagenesis Using Histone-miniSOG in C. elegans

    Published on: November 14, 2016

    Gene Trapping Using Gal4 in Zebrafish
    13:34

    Gene Trapping Using Gal4 in Zebrafish

    Published on: September 29, 2013

    Area of Science:

    • Genomics
    • Molecular Biology
    • Medical Genetics

    Background:

    • The Human Genome Project, a 13-year international research effort, aimed to determine the sequence of nucleotide base pairs that make up human DNA.
    • Understanding the complete human genetic blueprint is crucial for deciphering the molecular basis of diseases.

    Purpose of the Study:

    • To summarize the impact of the Human Genome Project on understanding gene-disease relationships.
    • To highlight the advancements in genetic research stemming from the project.

    Main Methods:

    • The Human Genome Project involved large-scale DNA sequencing and data analysis.
    • Bioinformatic approaches were essential for interpreting the vast amount of genetic data.

    Main Results:

    • The project successfully sequenced the entire human genome, providing a comprehensive reference.
    • It identified numerous genes and genetic variations associated with various diseases.

    Conclusions:

    • The Human Genome Project revolutionized our comprehension of human genetics and disease.
    • It laid the groundwork for personalized medicine and targeted therapeutic strategies.