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Updated: Jul 1, 2026

An Olfactory Preference Test for Measuring Olfactory Hedonic Biases in Mouse Models of Depression
Published on: July 11, 2025
Depressive symptoms and olfactory function in older adults
Anna Scinska1, Elzbieta Wrobel, Agnieszka Korkosz
1Department of Otolaryngology, Warsaw Medical Academy, Warsaw, Poland. scinska@ipin.edu.pl
Aims:
Neuroimaging studies suggest a significant overlap between brain regions involved in the regulation of olfaction and mood. The aim of the present study was to search for correlations between depressive symptomatology measured by the 15-item Geriatric Depression Scale (GDS) and olfactory function assessed with Sniffin' Sticks in non-demented older adults (aged 53-79 years).
Methods:
Taste detection thresholds were also measured by means of electrogustometry on the anterior tongue.
Results:
No correlation was found between the GDS scores (range: 0-12) and olfactory thresholds or olfactory identification scores. Similarly, there was no relationship between depressive symptoms and electrogustometric thresholds. Subjects (n = 25) scoring > or = 5 on the GDS were classified as 'depressed' and all other individuals (n = 60) were classified as 'non-depressed'. The two groups did not differ in terms of the olfactory measures and electrogustometric threshold.
Conclusion:
Depressive symptoms are not associated with any major olfactory deficit in non-clinical older adults.
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