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Updated: Jul 1, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
Migraine at all ages
Marcelo E Bigal1, Richard B Lipton
1Albert Einstein College of Medicine, Department of Neurology, 1165 Morris Park Avenue, Bronx, NY 10451, USA. mbigal@aecom.yu.edu
Abstract:
Although the influence of age on the prevalence of migraine is well known, the clinical characterization of migraine across the lifespan remains poorly studied. Limited evidence suggests that migraine attacks get shorter and less typical with advancing age. Similar results were found for transformed migraine at different ages. In this article, we first discuss the prevalence and clinical features of episodic migraine. We then discuss the epidemiology and profile of transformed migraine across the lifespan. Clarifying the influence of age on migraine is of importance for clinical diagnosis and treatment. It also may contain clues to evolving disease biology.
Insights
Migraine characteristics change with age, with attacks becoming shorter and less typical in older adults. Understanding these age-related migraine patterns is crucial for diagnosis and treatment.
Area of Science:
- Neurology
- Gerontology
- Epidemiology
Background:
- The prevalence of migraine is known to be influenced by age.
- However, the clinical characteristics of migraine throughout the lifespan are not well understood.
- Existing research suggests migraine attacks may shorten and become less typical as individuals age.
Purpose of the Study:
- To review the prevalence and clinical features of episodic migraine.
- To examine the epidemiology and characteristics of transformed migraine across different age groups.
- To clarify how age influences migraine for improved clinical diagnosis and treatment.
Main Methods:
- Literature review focusing on episodic migraine prevalence and clinical features.
- Epidemiological analysis of transformed migraine across the lifespan.
- Synthesis of current evidence on age-related changes in migraine presentation.
Main Results:
- Migraine attacks tend to become shorter and less typical with advancing age.
- Transformed migraine also exhibits age-related variations in its presentation.
- Age significantly impacts migraine prevalence and clinical characteristics.
Conclusions:
- Age is a critical factor influencing migraine presentation and epidemiology.
- Understanding age-specific migraine patterns is essential for accurate diagnosis and effective treatment strategies.
- Further research into age-related migraine biology may reveal new therapeutic targets.
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