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Updated: Jul 1, 2026

Epigenetic Regulation of Cardiac Differentiation of Embryonic Stem Cells and Tissues
Published on: June 3, 2016
Transcriptional and epigenetic regulations of embryonic stem cells
Jia-Hui Ng1, Jian-Chien Dominic Heng, Yuin-Han Loh
1Gene Regulation Laboratory, Genome Institute of Singapore, Singapore 138672, Singapore.
Abstract:
Embryonic stem cells (ESCs) are characterized by their broad developmental potential and the capacity to self-renew. The advent of high-throughput technologies has facilitated genome-wide studies of transcriptional network, resulting in an ever-increasing repertoire of transcription factors implicated in the maintenance of the embryonic stem cell state. While the transcriptional circuitry continues to expand, epigenetic regulation has also gained attention as an important process in stem cell function. Herein, we discuss the recent advancements made in understanding the transcriptional and epigenetic regulations of embryonic stem cells.
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