Related Experiment Video
Updated: Jul 1, 2026

Hyperglycemic Clamp and Hypoglycemic Clamp in Conscious Mice
Published on: January 26, 2024
Relationship between hypomagnesemia and glucose homeostasis
Martina Montagnana1, Giuseppe Lippi, Giovanni Targher
1Sezione di Chimica Clinica, Dipartimento di Scienze Morfologico-Biomediche, Università di Verona, Italy. martina.montagnana@med.lu.se
Background:
Controversial data are available on the relationship between magnesium metabolism and glucose homeostasis.
Methods:
We performed a retrospective analysis to retrieve results of serum magnesium and fasting plasma glucose (FPG) tests (7,659 outpatients >35 years old).
Results:
Subjects with FPG value > 7.0 mmol/L were more likely to had hypomagnesemia. The frequency of hypomagnesemia was also significantly higher among those with high FPG values > 7.0 mmol/L. In multivariable linear regression analysis, magnesium was significantly associated with FPG only in patients with FPG > 7.0 mmol/L.
Conclusions:
Magnesium metabolism could be implicated in the glucose homeostasis, especially in patients with FPG values suggestive for diabetes.
Related Concept Videos
Hypoglycemia and Glucagon
Hypoglycemia
Hyperglycemia
Glucose Homeostasis: Regulation of Blood Glucose
During fasting, when blood glucose levels are low, the pancreas secretes glucagon. it...
Hyperosmolar Hyperglycemic State
Diabetic Ketoacidosis ll: Pathophysiology

