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Updated: Jul 1, 2026

A Guided Materials Screening Approach for Developing Quantitative Sol-gel Derived Protein Microarrays
Published on: August 26, 2013
Solid phase microextraction fibers coated with sol-gel aminopropylsilica/polydimethylsiloxane: development and its
André F P Biajoli1, Fabio Augusto
1Institute of Chemistry, State University of Campinas (Unicamp), Campinas-SP 13084-971, Brazil.
Abstract:
The preparation and applicability of solid phase microextraction (SPME) fibers coated with a sol-gel organically modified silica based on 3-aminopropyltrimethoxysilane and polydimethylsiloxane (APTMS/PDMS) are described here. Micrographs of the coated fibers revealed a rugous surface; the thickness of the coating was estimated to be less than 30 microm. The APTMS/PDMS fibers were tested with synthetic samples and compared to commercial fibers for headspace SPME analysis of beer. Extraction and desorption using the APTMS/PDMS fibers were faster, which is typical for sol-gel SPME fibers. For polar and semi-polar compounds on beer headspace, the extraction efficiencies of the APTMS/PDMS fiber were superior to those of conventional fibers. The APTMS/PDMS fiber was found to be capable of extracting a broad range of analytes, including highly polar acidic species such as organic acids.
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