Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 1, 2026

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy
07:51

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy

Published on: June 1, 2019

Correct identification of a sentinel node postselective lymphadenectomy using antimony levels.

Marc Moncrieff1, Richard Scolyer, John Thompson

  • 1The Sydney Melanoma Unit, North Sydney, New South Wales, Australia. marc@moncrieff.net

Melanoma Research
|September 11, 2008
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Standard neoadjuvant immunotherapy in patients with resectable stage III Melanoma - The early Australian experience.

European journal of cancer (Oxford, England : 1990)·2026
Same author

Targeted removal of soluble Fms-like tyrosine kinase 1 in very preterm preeclampsia: a pilot trial.

Nature medicine·2026
Same author

Postpartum readmission for maternal infection or neonatal adverse events in women randomised to outpatient balloon versus inpatient prostaglandin for induction of labour: a post-trial follow up study.

BMC pregnancy and childbirth·2026
Same author

The impact of next generation sequencing studies on the diagnosis of BAP1 inactivated melanocytic tumors.

Human pathology·2026
Same author

Race is a Contributing Factor to Clinico-Pathological Characteristics of Ameloblastoma at a Multi-Network Academic Hospital System.

Journal of racial and ethnic health disparities·2026
Same author

A cost comparison of radiotherapy and topical imiquimod for lentigo maligna treatment: Considerations for clinical decision-making.

Journal of the American Academy of Dermatology·2025

A novel technique using antimony levels in paraffin-embedded tissue specimens resolved uncertainty in identifying sentinel lymph nodes after lymphadenectomy. This method aids clinical decision-making in complex surgical cases.

Area of Science:

  • Oncology
  • Surgical Pathology
  • Analytical Chemistry

Background:

  • Sentinel lymph node biopsy is crucial for cancer staging.
  • Accurate sentinel lymph node identification can be challenging post-lymphadenectomy.
  • Current methods may face limitations in specific clinical scenarios.

Observation:

  • A case report presented uncertainty in identifying the sentinel lymph node after lymphadenectomy.
  • Tissue paraffin-embedded specimens were available for analysis.
  • A novel analytical technique was employed.

Findings:

  • The study utilized a novel technique to measure antimony levels in paraffin-embedded lymph node specimens.
  • This method successfully differentiated the sentinel lymph node, resolving diagnostic uncertainty.

More Related Videos

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
05:52

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy

Published on: August 19, 2021

Related Experiment Videos

Last Updated: Jul 1, 2026

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy
07:51

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy

Published on: June 1, 2019

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
05:52

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy

Published on: August 19, 2021

  • This represents the first application of this technique for clinical decision support.

    • Implications:

    • This antimony-based analysis offers a new tool for sentinel lymph node identification.
    • The technique has the potential to improve accuracy in cancer staging and treatment planning.
    • Further validation could establish this method as a standard in surgical pathology.