Related Experiment Video
Updated: Jul 1, 2026
10:12
Three Dimensional Vestibular Ocular Reflex Testing Using a Six Degrees of Freedom Motion Platform
Published on: May 23, 2013
[Stress-related vertical double vision and ptosis]
A M Palmowski-Wolfe1, L Kappos, J Müller-Brand
1Augenklinik, Universitätsspital Basel, Basel, Schweiz. PalmowskiA@uhbs.ch
Summary
A patient with sphenoid meningioma experienced eyelid drooping and double vision. Radiopeptide therapy with (90)Y-DOTATOC successfully reduced tumor volume and improved symptoms.
Area of Science:
- Neuro-oncology
- Radiology
- Ophthalmology
Background:
- Sphenoid meningiomas are rare tumors that can cause significant neurological and visual symptoms.
- Eyelid drooping (ptosis), diplopia, and photophobia are potential clinical manifestations.
Observation:
- A 43-year-old female presented with progressive left eyelid ptosis, intermittent diplopia, and photophobia over 2-3 months.
- Diagnostic imaging confirmed the presence of a sphenoid meningioma.
Findings:
- The patient underwent two cycles of radiopeptide therapy using Yttrium-90 labeled octreotate ((90)Y-DOTATOC).
- Treatment resulted in a notable reduction in tumor volume.
- Clinical symptoms, including ptosis and diplopia, showed significant improvement and subsequent stabilization.
Implications:
- Radiopeptide therapy with (90)Y-DOTATOC is a viable treatment option for sphenoid meningiomas.
- This therapeutic approach offers potential for tumor volume reduction and symptomatic relief in patients with neuroendocrine tumors.
- Further research into targeted radionuclide therapy for meningiomas is warranted.
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