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Detection of Functional Matrix Metalloproteinases by Zymography
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Structural bases for substrate and inhibitor recognition by matrix metalloproteinases

Loretta Aureli1, Magda Gioia, Ilaria Cerbara

  • 1Colosseum Combinatorial Chemistry Centre for Technology (C4T S.C.a r.l.), Via della Ricerca Scientifica s.n.c, I-00133 Roma, Italy. loretta.aureli@uniroma2.it

Current Medicinal Chemistry
|September 11, 2008
PubMed
Summary

Matrix metalloproteinases (MMPs) are enzymes crucial for extracellular matrix remodeling. Understanding their structure-function relationships can guide the development of more effective MMP inhibitors for various diseases.

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