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A computer program that simulates cloning of DNA.

E J Shillitoe1

  • 1Department of Microbiology, University of Texas Health Science Center, Houston 77225.

Biotechniques
|June 1, 1991
PubMed
Summary

Easy Cloner is a free computer program for manipulating DNA sequences and generating plasmid maps for cloning experiments. Operated via mouse in graphics mode on IBM PC compatibles, it simplifies molecular biology workflows.

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Area of Science:

  • Molecular Biology
  • Bioinformatics
  • Computational Biology

Background:

  • DNA sequence manipulation is crucial for molecular cloning.
  • Visualizing resulting plasmids aids experimental design.
  • Accessible software tools enhance research capabilities.

Purpose of the Study:

  • To introduce Easy Cloner, a user-friendly software for DNA manipulation.
  • To demonstrate plasmid mapping functionalities.
  • To provide a public domain tool for cloning experiments.

Main Methods:

  • Utilizes IBM PC compatible graphics mode.
  • Operated through a mouse-driven graphical user interface.
  • Focuses on DNA sequence manipulation and plasmid map generation.

Main Results:

  • Easy Cloner effectively manipulates DNA sequences.
  • The program generates accurate maps of resulting plasmids.
  • It offers an intuitive interface for researchers.

Conclusions:

  • Easy Cloner provides a valuable, accessible tool for DNA cloning and plasmid analysis.
  • The software simplifies complex molecular biology tasks.
  • Its public domain status promotes widespread adoption in research.

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