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The CYP2B2 5' flank contains a complex glucocorticoid response unit

Etienne Audet-Walsh1, Antoine Amaury Lachaud, Alan Anderson

  • 1Centre de recherche en cancérologie de l'Université Laval, L'Hôtel-Dieu de Québec, CHUQ, Québec, Canada.

Biochemical Pharmacology
|September 11, 2008
PubMed
Summary

Dexamethasone induces CYP2B genes through a complex glucocorticoid response unit. Constitutive androstane receptor (CAR) acts as an accessory factor in this dexamethasone response, enhancing both basal and induced levels.

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