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Normothermic Ex Situ Heart Perfusion in Working Mode: Assessment of Cardiac Function and Metabolism
Published on: January 12, 2019
Achieving metrics during beating-heart ex-maze procedures improves outcomes
Andy C Kiser1, Gerhard Wimmer-Greinecker, Boguslaw Kapelak
1FirstHealth Arrhythmia Center, Pinehurst, NC, USA. akiser@firsthealth.org
The Heart Surgery Forum
|September 11, 2008
Summary
The beating-heart extracardiac maze (Ex-Maze) procedure shows high success rates for atrial fibrillation (AF) treatment. Spontaneous rhythm conversion and confirmed pulmonary vein block during surgery predict excellent long-term outcomes.
Area of Science:
- Cardiovascular Surgery
- Cardiac Electrophysiology
- Minimally Invasive Cardiac Procedures
Background:
- Current surgical treatments for atrial fibrillation (AF) lack intraoperative metrics to predict long-term outcomes.
- The extracardiac maze (Ex-Maze) procedure offers a beating-heart approach to AF treatment.
- Spontaneous conversion to sinus rhythm (SR) and pulmonary vein exit block are key predictors of AF freedom.
Purpose of the Study:
- To evaluate the efficacy of the beating-heart Ex-Maze procedure in patients undergoing concomitant cardiac surgery.
- To assess the correlation between intraoperative spontaneous rhythm conversion and pulmonary vein exit block with long-term AF freedom.
Main Methods:
- A beating-heart Ex-Maze procedure was performed in 54 AF patients undergoing various cardiac surgeries.
- A comprehensive, biatrial epicardial ablation pattern was created using unipolar, radiofrequency energy.
- Electrocardiogram and 24-hour Holter monitor data were collected intraoperatively and postoperatively up to 12 months.
Main Results:
- 32 of 48 patients (67%) spontaneously converted to SR during lesion creation.
- At a mean follow-up of 262 days, 88% of patients were free from AF, and 74% discontinued antiarrhythmic drugs.
- Pulmonary vein exit block was confirmed in 97% of tested patients, with 97% freedom from AF in this subgroup.
Conclusions:
- The Ex-Maze procedure enables creation of a comprehensive biatrial lesion pattern on a beating heart.
- Intraoperative observation of spontaneous conversion to SR and confirmed pulmonary vein exit block are crucial metrics for predicting successful long-term AF management.
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