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Updated: Jul 1, 2026

Human Circadian Phenotyping and Diurnal Performance Testing in the Real World
Published on: April 7, 2020
[In time for Beijing: influence of the biological clock on athletic performance]
J H Meijer1, T Deboer, S Michel
1Leids Universitair Medisch Centrum, Laboratorium voor Neurofysiologie, afd. Moleculaire Celbiologie, Postbus 9600, 2300 RC Leiden. j.h.meijer@lumc.nl
Abstract:
Circadian rhythms are a common characteristic ofmulticellular organisms and evolved as an adaptation to the earth's rotation on its axis. In humans, circadian rhythms are regulated by suprachiasmatic nuclei located at the base of the hypothalamus. The suprachiasmatic nuclei function as a biological clock that controls the daily rhythms of nearly all physiological functions. External light synchronises the endogenous clock to the environmental light-dark cycle. When travelling rapidly across multiple time zones, the endogenous clock must adjust to the new time. During the period of adjustment, many physiological circadian rhythms become desynchronised and jet lag occurs. Few studies have analysed the influence of jet lag on athletic performance. These studies indicate that performance levels can decline during jet lag. This seems to be a result of the desynchronized physiological state and sleep disturbances, leading to suboptimal values of blood pressure, heart rate, body temperature, and muscle strength. We give some advice for athletes who must cross multiple time zones shortly before a competition.
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