Effect of the mineralizing agent on the permanent teeth

Area of Science:

• Pediatric Dentistry
• Cariology
• Preventive Dentistry

Background:

• Dental caries (DFS) and enamel fluorosis lesions (EFDS) are significant concerns in children's oral health.
• Early intervention strategies are crucial for managing early childhood caries and enamel defects.

Purpose of the Study:

• To evaluate the efficacy of a novel mineralizing agent in preventing dental caries and enamel fluorosis in children.
• To assess the age-related clinical effects of the mineralizing agent on permanent teeth.

Main Methods:

• A two-year pragmatic clinical trial involving 7-year-old Finnish children with low DFS prevalence.
• Biweekly mouthrinsing with a 2% mineralizing agent and 0.2% NaF solution in the test group.
• Control group received biweekly placebo and 0.2% NaF solutions.

Main Results:

• The test group showed a high percentage reduction in the increment of both EFDS and DFS.
• The control group exhibited no significant difference in caries incidence compared to the normal rate for the age cohort.
• A positive clinical effect was observed, linked to remineralization of existing lesions and inhibition of new ones.

Conclusions:

• The tested mineralizing agent demonstrates significant preventive effects against dental caries and enamel fluorosis in children.
• The treatment's efficacy is age-dependent and promotes tooth remineralization and lesion inhibition.
• This mineralizing agent represents a promising approach for pediatric dental caries prevention.