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Updated: Jul 1, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
Unilateral or "side-locked" migrainous headache with autonomic symptoms linked to night guard use
Jean Strahlendorf1, Randolph Schiffer, Howard Strahlendorf
1Texas Tech University Health Sciences Center - Cell Physiology and Molecular Biophysics, Lubbock, TX 79430, USA.
Abstract:
Night guards are commonly prescribed as a palliative measure for bruxism, temporomandibular joint symptoms, and associated disorders. We describe a patient with a 10- to 12-year history of night guard use with concurrent unilateral side-locked migrainous headaches with autonomic symptoms characteristic of trigeminal autonomic cephalgia. These headaches were refractory to numerous pharmacological interventions. Upon self-initiated cessation of night guard use, there was complete remission of headaches. We believe the headaches were initiated by night guard-initiated irritation of the trigeminal nerve and a trigeminal autonomic reflex resulting in unilateral migrainous headache with autonomic signs.
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