Related Experiment Video
Updated: Jul 1, 2026
Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
Published on: April 12, 2019
Primary osteogenic sarcoma of the breast: A case report
Shabuddin Khan1, Ewen A Griffiths, Nigam Shah
1Department of General Surgery, Blackpool Victoria Hospital, Blackpool Fylde and Wyre NHS Trust, Blackpool, FY2 8NR, UK. mr.ravi@bfwhospitals.nhs.uk.
Introduction:
Primary osteosarcoma of the breast is a rare malignant tumour. It is typically a poor prognosis tumour, which has some interesting features worthy of discussion. We report a case of primary osteosarcoma of the breast and summarise the previous medical literature to highlight several details of this unusual tumour.
Case Presentation:
A 66-year-old Caucasian lady presented with painless lump in her right breast. Mammography showed features of fibroadenoma with calcification and fine needle aspiration cytology was reported as showing malignant cells (C5). Wide local excision was performed and histological features were consistent with primary osteosarcoma with predominance of osteoclastic activity. Subsequent completion mastectomy was performed because of suspicion of incomplete excision. She remains disease free 8 years from her initial surgery.
