Related Experiment Video
Updated: Jul 1, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
The Infant Behavioral Assessment and Intervention Program for very low birth weight infants at 6 months corrected age
Karen Koldewijn1, Marie-Jeanne Wolf, Aleid van Wassenaer
1Department of Rehabilitation, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. k.koldewijn@amc.uva.nl
Insights
The Infant Behavioral Assessment and Intervention Program (IBAIP) significantly improved developmental and neurobehavioral outcomes for very low birth weight (VLBW) infants. VLBW infants receiving the IBAIP intervention showed enhanced mental, motor, and behavioral development at six months corrected age.
Area of Science:
- Neonatal Development
- Behavioral Pediatrics
- Developmental Psychology
Background:
- Very low birth weight (VLW) infants face developmental and neurobehavioral challenges.
- Early interventions are crucial for optimizing outcomes in this vulnerable population.
- Self-regulatory competence is a key factor in infant development.
Purpose of the Study:
- To evaluate the effectiveness of the Infant Behavioral Assessment and Intervention Program (IBAIP).
- To determine if IBAIP improves developmental and neurobehavioral outcomes in very low birth weight (VLW) infants.
- To assess the impact of IBAIP on infants' self-regulatory competence.
Main Methods:
- Randomized controlled trial with 86 infants in the intervention group and 90 in the control group.
- Intervention included home visits from discharge until 6 months corrected age.
- Developmental and neurobehavioral assessments conducted using Bayley Scales of Infant Development-II (BSID-II) and Infant Behavioral Assessment (IBA).
Main Results:
- Intervention group showed significant improvements in Mental Developmental Index (+7.2 points) and Psychomotor Developmental Index (+6.4 points) after adjustment.
- The Behavioral Rating Scale of the BSID-II and the IBA also favored the intervention group, indicating more approach behaviors and less stress.
- These positive effects were observed at 6 months corrected age.
Conclusions:
- The Infant Behavioral Assessment and Intervention Program (IBAIP) is effective in enhancing the development of very low birth weight (VLW) infants.
- IBAIP positively impacts mental, motor, and behavioral outcomes.
- The findings support the use of IBAIP for supporting self-regulatory competence in VLBW infants.
Objective:
To determine whether the Infant Behavioral Assessment and Intervention Program (IBAIP), designed to support and enhance infants' self-regulatory competence, improved developmental and neurobehavioral outcomes in very low birth weight (VLBW) infants.
Study Design:
We randomized 86 infants to 1 intervention before discharge and to 6 to 8 home interventions until 6 months corrected age, and 90 control infants received standard care. Developmental and behavioral outcomes were evaluated at 6 months corrected age with the Bayley Scales of Infant Development-II (BSID-II). Neurobehavioral functioning was evaluated with the Infant Behavioral Assessment (IBA) at baseline and at 6 months corrected age.
Results:
Despite randomization, some differences in neonatal characteristics were found between the intervention and control infants. After adjustment, intervention effects of 7.2 points (+/- standard error 3.1) on the Mental Developmental Index and 6.4 +/- 2.4 points on the Psychomotor Developmental Index favored the intervention infants. The Behavioral Rating Scale of the BSID-II (P = .000) and the IBA (more approach [P = .003] and less stress [P = .001] over time) also favored the intervention infants.
Conclusions:
The IBAIP improved the mental, motor, and behavioral outcomes of VLBW infants at 6 months corrected age.
