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Related Experiment Video

Updated: Jul 1, 2026

Synergizing Antegrade Endoscopic with Bridging Vein Harvesting for Improvement of Great Saphenous Vein Graft Quality from the Lower Leg
09:04

Synergizing Antegrade Endoscopic with Bridging Vein Harvesting for Improvement of Great Saphenous Vein Graft Quality from the Lower Leg

Published on: November 19, 2019

Early results for below-knee bypasses using Distaflo.

Iosif Gulkarov1, Rajesh Malik, Rakhsim Yakubov

  • 1Department of Surgery, New York University School of Medicine, New York 10016, USA.

Vascular and Endovascular Surgery
|September 12, 2008
PubMed
Summary

The Distaflo graft, a modified polytetrafluoroethylene prosthesis, offers a viable option for lower extremity revascularization when autologous veins are unavailable. It shows promising patency and limb salvage rates for below-knee popliteal and tibial bypasses.

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Vein Interposition Model: A Suitable Model to Study Bypass Graft Patency
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Vein Interposition Model: A Suitable Model to Study Bypass Graft Patency
07:22

Vein Interposition Model: A Suitable Model to Study Bypass Graft Patency

Published on: January 15, 2017

Area of Science:

  • Vascular Surgery
  • Biomaterials Science
  • Regenerative Medicine

Background:

  • Prosthetic grafts are alternatives for lower extremity revascularization but have limited patency, especially infrageniculate reconstructions.
  • Polytetrafluoroethylene (PTFE) grafts were geometrically modified to improve patency.
  • Autologous vein conduits are preferred but not always available.

Purpose of the Study:

  • To evaluate the efficacy of the geometrically modified Distaflo PTFE graft for infrageniculate lower extremity bypass.
  • To assess patency rates and limb salvage in patients undergoing below-knee popliteal and tibial bypasses using the Distaflo graft.

Main Methods:

  • A retrospective chart review of 57 patients who underwent 60 lower extremity bypasses using the Distaflo graft between June 2003 and April 2006.
  • Grafts were placed to below-knee popliteal (28) and tibial (24) outflow sites, with 8 to above-knee popliteal.
  • Follow-up included assessment of primary, assisted primary, and secondary patency, and limb salvage.

Main Results:

  • Distaflo bypass was performed at the infrageniculate level in 86.7% of cases.
  • At 1 year, below-knee popliteal bypasses showed primary, assisted primary, and secondary patency rates of 83.5%, 89.5%, and 94.7%, respectively.
  • Tibial bypasses achieved 1-year primary, assisted primary, and secondary patency rates of 44.4%, 44.4%, and 63.2%, respectively, with a limb salvage rate of 74.9%.

Conclusions:

  • The Distaflo precuffed graft is a suitable alternative conduit for below-knee popliteal and tibial lower extremity reconstructions when autologous veins are unavailable.
  • The graft demonstrates promising early patency and limb salvage rates, even for tibial bypasses.
  • Further research may explore long-term outcomes and comparisons with other prosthetic materials.