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Updated: Jul 1, 2026

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Droplet Barcoding-Based Single Cell Transcriptomics of Adult Mammalian Tissues
Published on: January 10, 2019
bold: The Barcode of Life Data System (http://www.barcodinglife.org)
Sujeevan Ratnasingham1, Paul D N Hebert
1Canadian Centre for DNA Barcoding, Biodiversity Institute of Ontario, University of Guelph Guelph, ON, Canada N1G 2W1.
Molecular Ecology Notes
|September 12, 2008
Summary
The Barcode of Life Data System (BOLD) is a free bioinformatics workbench for DNA barcoding data. It integrates molecular, morphological, and distribution data, aiding research and publication in global sequence databases.
Area of Science:
- Bioinformatics
- Genomics
- Molecular Biology
Background:
- DNA barcoding is crucial for species identification and biodiversity assessment.
- Integrating diverse data types (molecular, morphological, distributional) presents a bioinformatics challenge.
- Existing platforms may not adequately support the comprehensive data assembly required for standardized DNA barcode records.
Purpose of the Study:
- To introduce the Barcode of Life Data System (BOLD) as a solution for DNA barcode data management.
- To describe the functional capabilities of BOLD in data acquisition, storage, analysis, and publication.
- To highlight BOLD's role in bridging traditional bioinformatics gaps and supporting research alliances.
Main Methods:
- The paper provides an overview of BOLD's informatics workbench.
- It details the system's capabilities for assembling molecular, morphological, and distributional data.
- Functional elements and data security models are discussed.
Main Results:
- BOLD serves as a comprehensive workbench for DNA barcode data.
- It facilitates the integration of diverse data types, addressing a bioinformatics chasm.
- The system supports the creation of standardized records for global sequence databases.
Conclusions:
- BOLD is a freely accessible, web-based platform essential for DNA barcoding research.
- Its flexible design supports broad research alliances and data publication.
- The system enhances the standardization and accessibility of biodiversity data.

