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Related Experiment Videos

Experimental methods of contraception.

G S Grubb1

  • 1Family Health International, Research Triangle Park, North Carolina.

Current Opinion in Obstetrics & Gynecology
|August 1, 1991
PubMed
Summary
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Novel contraceptives with unique mechanisms are advancing. These include hormonal therapies like mifepristone and Centchroman, gonadotropin antagonists, reversible vas occlusion, and immunocontraceptives for targeted fertility control.

Area of Science:

  • Reproductive medicine
  • Contraceptive development
  • Pharmacology

Background:

  • Most current contraceptives utilize existing agents in new delivery systems.
  • Several novel contraceptives with distinct mechanisms of action are progressing.
  • Innovation in fertility control is crucial for reproductive health.

Purpose of the Study:

  • To review emerging contraceptive technologies with novel mechanisms of action.
  • To highlight advancements in both female and male contraceptive development.
  • To discuss the potential impact of these new methods on reproductive health.

Main Methods:

  • Review of ongoing research and development in contraceptive science.
  • Analysis of clinical trial progress for novel agents and devices.

Related Experiment Videos

  • Examination of pharmacological and immunological approaches to fertility control.

    • Main Results:

    • Mifepristone (RU 486) is being investigated as an ovulation inhibitor, monthly pill, and postcoital contraceptive.
    • Centchroman, a nonsteroidal antiestrogen, is available as a weekly pill in India.
    • Potent pituitary gonadotropin antagonists show promise for inhibiting ovulation and spermatogenesis.
    • A removable intraluminal vas occlusion plug is under development for male contraception.
    • Immunocontraceptives targeting eggs or sperm represent a highly specific future approach.

    Conclusions:

    • Significant progress is being made in developing contraceptives with novel mechanisms.
    • These advancements offer diverse options for future family planning and reproductive health.
    • Targeted approaches like immunocontraceptives and reversible vas occlusion show great promise.