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Related Experiment Video

Updated: Jul 1, 2026

Encapsulated Cell Technology for the Delivery of Biologics to the Mouse Eye

Encapsulated Cell Technology for the Delivery of Biologics to the Mouse Eye

Published on: March 30, 2020

Patency and Agile capsules.

Angel Caunedo-Alvarez¹, Javier Romero-Vazquez, Juan-M Herrerias-Gutierrez

¹Gastroenterology Service, "Virgen Macarena" University Hospital, Avda. Dr. Fedriani, Seville 41071, Spain. acaunedoa@meditex.es

World Journal of Gastroenterology

|September 12, 2008

Summary

The Patency capsule assesses small bowel patency non-invasively. A new Agile capsule minimizes occlusion risks, even in tight strictures, improving patient safety for capsule endoscopy.

Area of Science:

Gastroenterology
Medical Devices
Diagnostic Imaging

Background:

Small bowel strictures are challenging to diagnose with current methods.
The Patency capsule offers a non-invasive approach to assess digestive tract patency.

Purpose of the Study:

To evaluate the efficacy of the Patency capsule in assessing small bowel patency.
To introduce the Agile capsule as a safer alternative to minimize occlusion risks.

Main Methods:

Clinical trials assessed the Patency capsule for functional small bowel patency.
Development of the Agile capsule with dual timer plugs for earlier disintegration.

Main Results:

Patency capsule trials show it's effective for identifying patients suitable for capsule endoscopy.

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Preparation of Multifunctional Silk-Based Microcapsules Loaded with DNA Plasmids Encoding RNA Aptamers and Riboswitches

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Some Patency capsule cases reported intestinal occlusion, necessitating surgery.

The Agile capsule initiates dissolution earlier and disintegrates even within tight strictures.

Conclusions:

The Patency capsule is a valuable tool for evaluating small bowel patency.
The Agile capsule enhances safety by reducing the risk of intestinal occlusion during patency testing.