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Updated: Jul 1, 2026

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Published on: May 29, 2020
The prevalence and accuracy of self-reported history of 11 autoimmune diseases
Glinda S Cooper1, Joan Wither, Tamara McKenzie
1United States Environmental Protection Agency, National Center for Environmental Assessment, Washington, DC 20460, USA. cooper.glinda@epa.gov
Objective:
To determine the prevalence and confirmation rate of autoimmune diseases reported by relatives of patients with lupus and controls.
Methods:
Medical histories were obtained by self-report from 626 first-degree relatives of lupus patients and 267 population controls.
Results:
Of 178 reports of an autoimmune disease, 44% were confirmed by medical records; excluding those whose medical records were unavailable, the confirmation rate was 76%. The prevalence of at least one confirmed autoimmune disease was 12% in lupus relatives and 2% in controls.
Conclusion:
Methods to improve the reliability of self-reported autoimmune disease history could enhance population and clinic-based research.
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