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A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level
Published on: January 19, 2024
[Effect of NaFeEDTA on hemoglobin level in iron deficient population: a systematic review]
Bo Wang1, Si-yan Zhan, Yin-yin Xia
1Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100083, China.
Objective:
To evaluate the effect of NaFeEDTA on hemoglobin level in iron deficient population.
Methods:
Comprehensive literature retrieval was performed via searching electronic databases, hand searching bibliographies of books and relevant journals, collecting grey literatures, looking into conference abstracts, contacting fields experts and reviewing references and citations. Criteria from Cochrane EPOC review group were used to assess the quality of included studies. Generic inverse variance method was used to undertake meta-analysis.
Results:
The pooled estimate for hemoglobin level (weighted mean difference) was 12.14 g/L (95% CI: 5.60-18.69; P < 0.001). Subgroup analysis indicated that lower baseline hemoglobin level and higher dose for intervention were associated to greater increase in hemoglobin level.
Conclusion:
This systematic review indicated that NaFeEDTA improved hemoglobin significantly in iron deficient population.
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