Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Synchronization effects in the pacemaker during high-frequency atrial stimulation].

E A Bogdanova

    Biulleten' Eksperimental'Noi Biologii I Meditsiny
    |May 1, 1991
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Assessment of the preventive effect of knockdown of cellular genes <i>NXF1</i>, PRPS1<i>PRPS1</i> and <i>NAA10</i> in influenza infection in an <i>in vitro</i> model.

    Voprosy virusologii·2025
    Same author

    Alternative Methods of Evaluation of Antimicrobial Activity of Breast Milk Serum.

    Bulletin of experimental biology and medicine·2021
    Same author

    Silicon-hydroxyapatite‒glycerohydrogel as a promising biomaterial for dental applications.

    Colloids and surfaces. B, Biointerfaces·2020
    Same author

    [Preparation of prokaryotic cDNA for high-throughput transcriptome analysis].

    Bioorganicheskaia khimiia·2012
    Same author

    [Application of the duplex-specific nuclease for fast analysis of single nucleotide polymorphisms and detection of target DNA in complex PCR products].

    Bioorganicheskaia khimiia·2011
    Same author

    [Experimental simulation of the structure of gastrointestinal microbial biocenosis].

    Vestnik Rossiiskoi akademii meditsinskikh nauk·2011

    This study on frog hearts reveals how atrial stimulation affects pacemaker synchronization. We observed how increased stimulation leads to ectopic rhythms and arrhythmias, offering insights into cardiac electrophysiology.

    Area of Science:

    • Cardiovascular Physiology
    • Cardiac Electrophysiology
    • Comparative Anatomy

    Context:

    • The study investigates the isolated frog heart's venous sinus pacemaker.
    • Focuses on the effects of suprathreshold atrial stimulation on cardiac rhythm.
    • Examines intervals between impulses during altered pacing frequencies.

    Purpose:

    • To analyze the succession of intra-impulse intervals in the frog heart's venous sinus.
    • To understand pacemaker synchronization patterns under varying atrial stimulation frequencies.
    • To identify the emergence of ectopic rhythms and arrhythmias.

    Summary:

    • Suprathreshold atrial stimulation at 15-200% above the intrinsic rate induced pacemaker synchronization with the stimulator.
    • Increased stimulation frequency led to retrograde atrial impulse conduction and established regular ectopic rhythms.

    Related Experiment Videos

  • Unilateral pacemaker acceleration and frequency convergence were observed in intermediate zones, alongside asymptotic and cyclic synchronization, manifesting as arrhythmias.

    • Impact:

    • Provides a detailed understanding of cardiac rhythm regulation and arrhythmogenesis in an isolated heart model.
    • Highlights the complex interplay between external stimulation and intrinsic cardiac pacemakers.
    • Offers potential insights into mechanisms underlying cardiac arrhythmias and synchronization phenomena.