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Tolterodine immediate release improves sexual function in women with overactive bladder
Sakineh Hajebrahimi1, Arash Azaripour, Homayoun Sadeghi-Bazargani
1Urology Department, Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.
The Journal of Sexual Medicine
|September 13, 2008
Summary
Tolterodine immediate release (IR) significantly enhances sexual function in women with overactive bladder (OAB). This treatment improved all aspects of sexual health, including desire, arousal, and satisfaction.
Area of Science:
- Urology
- Sexual Health
- Pharmacology
Background:
- Overactive bladder (OAB) significantly impacts quality of life, exceeding the negative effects of conditions like diabetes.
- OAB detrimentally affects female sexual health more than urinary incontinence.
- Tolterodine immediate release (IR) is known to improve OAB urinary symptoms.
Purpose of the Study:
- To assess the effect of tolterodine IR on the sexual function of women diagnosed with OAB.
- To quantify improvements in sexual health domains following tolterodine IR treatment.
Main Methods:
- A study involving 30 sexually active women (ages 20-52) with OAB.
- Patients completed the International Consultation on Incontinence Questionnaire (ICIQ) and Arizona Sexual Experience Scale (ASEX) at baseline and monthly for 3 months.
- Changes in ICIQ and ASEX scores were analyzed to evaluate treatment efficacy.
Main Results:
- The mean total ASEX score showed significant improvement at 1, 2, and 3 months post-treatment (P<0.01).
- Significant improvements were observed in sexual desire, arousal, vaginal lubrication, orgasm, and orgasm satisfaction (P<0.01).
Conclusions:
- Tolterodine IR demonstrates a significant positive impact on the sexual function of women suffering from OAB.
- The study confirms that tolterodine IR improves all evaluated domains of female sexual health in OAB patients.
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