Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diencephalon: Thalamus and Information Relay01:27

Diencephalon: Thalamus and Information Relay

The thalamus, often called “the gateway to the cerebral cortex,” is vital in processing and directing sensory and motor signals throughout the brain. Almost all inputs destined for the cerebral cortex, except for olfactory signals, are relayed through the thalamus. The thalamus is  a sophisticated relay station, channeling information from various brain regions to the cerebral cortex, as well as a filter, prioritizing certain signals over others based on current physiological states or needs.
Functional Brain Systems: Limbic System01:15

Functional Brain Systems: Limbic System

The limbic system, often called the "emotional brain," is a complex set of structures located deep within the brain. The intricate network of the limbic system supports a wide range of psychological functions, from emotional regulation to memory formation and sensory processing. This functional brain region encompasses specific parts of the diencephalon and the cerebrum, integrating the higher mental functions of the cerebral cortex with the primitive emotional responses of the deep brain...
Diencephalon: Hypothalamus and Coordination01:23

Diencephalon: Hypothalamus and Coordination

The hypothalamus is a small yet highly complex and essential brain region that plays a crucial role in regulating various bodily functions. Anatomically, it is located at the base of the brain, just above the brainstem and below the thalamus, forming part of the limbic system.
The hypothalamus interacts with other brain regions, including the pituitary gland, through a direct physical connection called the hypothalamic-pituitary axis. The hypothalamus receives somatic and visceral inputs and...
Diencephalon: Anatomical Regions01:30

Diencephalon: Anatomical Regions

The diencephalon, etymologically translated as 'through brain,' plays an integral role as the conduit between the cerebrum and the vast extent of the nervous system. However, the olfactory system is an exception, as it interfaces directly with the cerebrum. The diencephalon, deeply ensconced beneath the cerebrum, primarily consists of three paired structures — the thalamus, hypothalamus, and epithelamus. It also includes accessory structures such as the subthalamus, which houses the subthalamic...
Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex.
Somatosensory, Motor, and Association Cortex01:23

Somatosensory, Motor, and Association Cortex

The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Toward a Pluralistic Model for the Schizophrenia Spectrum-Dopamine and Beyond.

JAMA psychiatry·2026
Same author

Parvalbumin and anxiety across development in female offspring of the MAM neurodevelopmental model of schizophrenia.

Journal of psychiatric research·2026
Same author

Associations of affective states and cognitive functions with eating behavior in healthy young Korean adults.

Physiology & behavior·2026
Same author

Antipsychotic drug action, novel treatment targets, and the failure of current clinical trial designs in evaluating new target molecules.

Biological psychiatry·2026
Same author

Addiction spectrum disorder: a conceptual framework for comprehensive understanding of addictive disorders.

Frontiers in psychology·2026
Same author

Prefrontal Cortex Dysfunction as a Precipitating Factor for Schizophrenia and Depression.

Journal of neurochemistry·2026

Related Experiment Video

Updated: Jul 1, 2026

Combined In Vivo Anatomical and Functional Tracing of Ventral Tegmental Area Glutamate Terminals in the Hippocampus
09:36

Combined In Vivo Anatomical and Functional Tracing of Ventral Tegmental Area Glutamate Terminals in the Hippocampus

Published on: September 9, 2020

Limbic and cortical information processing in the nucleus accumbens.

Yukiori Goto1, Anthony A Grace

  • 1Department of Psychiatry, McGill University, Montreal, Quebec, H3A 1A1, Canada. yukiori.goto@mcgill.ca

Trends in Neurosciences
|September 13, 2008
PubMed
Summary

The nucleus accumbens integrates limbic and prefrontal information to guide goal-directed behaviors. Understanding its function is key to treating addiction and psychiatric disorders.

More Related Videos

Perceptual and Category Processing of the Uncanny Valley Hypothesis' Dimension of Human Likeness: Some Methodological Issues
07:34

Perceptual and Category Processing of the Uncanny Valley Hypothesis' Dimension of Human Likeness: Some Methodological Issues

Published on: June 3, 2013

Related Experiment Videos

Last Updated: Jul 1, 2026

Combined In Vivo Anatomical and Functional Tracing of Ventral Tegmental Area Glutamate Terminals in the Hippocampus
09:36

Combined In Vivo Anatomical and Functional Tracing of Ventral Tegmental Area Glutamate Terminals in the Hippocampus

Published on: September 9, 2020

Perceptual and Category Processing of the Uncanny Valley Hypothesis' Dimension of Human Likeness: Some Methodological Issues
07:34

Perceptual and Category Processing of the Uncanny Valley Hypothesis' Dimension of Human Likeness: Some Methodological Issues

Published on: June 3, 2013

Area of Science:

  • Neuroscience
  • Behavioral Neuroscience
  • Psychiatric Research

Background:

  • The nucleus accumbens is crucial for regulating goal-directed behaviors.
  • It integrates information from limbic structures and the prefrontal cortex.
  • Dysregulation in these processes is implicated in addiction and psychiatric disorders.

Purpose of the Study:

  • To provide an integrated view of information processing control in the nucleus accumbens.
  • To explore the role of nucleus accumbens function in goal-directed behaviors.
  • To understand how disruptions contribute to pathological states like addiction and psychiatric disorders.

Main Methods:

  • Review of recent studies on nucleus accumbens function.
  • Analysis of limbic-system interactions within the nucleus accumbens.
  • Examination of dopamine's modulatory role.

Main Results:

  • The nucleus accumbens integrates diverse neural inputs to regulate behavior.
  • Dopamine plays a significant role in modulating these interactions.
  • Disruptions in these pathways are linked to psychiatric pathophysiology.

Conclusions:

  • A proposed model integrates findings on nucleus accumbens function and limbic interactions.
  • The model accounts for dopamine's modulatory effects.
  • Testable hypotheses are provided for understanding the pathophysiology of major psychiatric disorders.