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Updated: Jul 1, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
Prioritising the prevention of medication handling errors.
Thilo Bertsche1, Dorothee Niemann, Yvonne Mayer
1Department of Internal Medicine VI, Clinical Pharmacology and Pharmacoepidemiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany. thilo.bertsche@med.uni-heidelberg.de
A new model effectively prioritizes medication handling errors in hospitals for prevention. This approach identifies high-risk errors, particularly in drug preparation and parenteral administration, to improve patient safety.
Area of Science:
- Hospital Pharmacy and Therapeutics
- Patient Safety and Quality Improvement
- Nursing Practice and Medication Management
Background:
- Medication errors are prevalent in hospital settings, frequently stemming from improper drug handling.
- Systematic strategies for preventing medication handling errors are currently lacking.
- A novel classification model was developed to categorize and prioritize these errors.
Purpose of the Study:
- To develop and apply a classification model for categorizing medication handling errors.
- To define the urgency of corrective actions based on error classification and risk assessment.
- To identify specific medication handling errors requiring immediate preventive strategies.
Main Methods:
- A prospective observational study was conducted on medical wards of a large teaching hospital.
- Prevalence of 20 predefined medication handling errors was evaluated, alongside nurses' knowledge deficits.
- Error severity was scored based on prevalence, potential risk, and drug type, informing a decision matrix for prioritizing interventions.
Main Results:
- 833 medication handling errors were detected across 1,376 observed processes.
- Preparation errors (0.88/process) were more frequent than administration errors (0.36/process); parenteral drugs (1.10/process) were more involved than enteral drugs (0.32/process).
- High-priority errors for intervention included enteral drug issues (light protection, prescribing information) and parenteral drug issues (incompatibilities, hygiene, administration duration, visual checks, prescribing information).
Conclusions:
- The developed classification model was successfully applied to prioritize medication handling errors.
- This systematic approach enables targeted prevention strategies to enhance medication safety.
- The findings highlight specific areas for quality improvement in drug handling within hospital settings.
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