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Published on: September 27, 2024
[Classification tree analysis in serous ovarian adenocarcinoma patients for prognostic factors associated with
Hong-Lan Zhu1, Yi Li, Yi-Ming Zhao
1Department of Gynecologic Cancer Center, People's Hospital, Peking University, Beijing 100044, China.
Objective:
To analyze the prognostic factors associated with three-year survival outcome in patients with serous ovarian adenocarcinoma by classification tree.
Methods:
Retrospectively we analyzed 81 cases with serous ovarian adenocarcinoma who had 3-year clinical outcomes and were hospitalized in People's Hospital from Jan 1991 to Dec 2003 by classification and regression trees (CART) software. Establish the classification tree.
Results:
Among the factors that were associated with the 3-year survival rate, age was the most important factor, other factors in turn were International Federation of Gynecology and Obstetrics (FIGO) stage, lymphoid metastasis, residual size after operation, chemotherapy and pathologic grade. By substitution variable analysis, it was demonstrated that there was cross interaction between age and residual size as well as age and chemotherapy.
Conclusion:
Age, FIGO stage, lymphoid metastasis, residual size after operation, chemotherapy and pathologic grade are important prognostic factors related with three-year survival probability of serous ovarian adenocarcinoma patients.
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