The structure of bergenin.

Area of Science:

• Natural Product Chemistry
• Structural Biology
• Crystallography

Background:

• Bergenin is a natural product with potential biological activities.
• Accurate structural determination is crucial for understanding compound properties and guiding further research.
• Previous structural assignments for bergenin derivatives require experimental validation.

Purpose of the Study:

• To confirm the established structure of bergenin 3,4,8,10,11-penta-acetate.
• To provide definitive structural evidence using X-ray diffraction.

Main Methods:

• Single-crystal X-ray diffraction analysis was performed on bergenin 3,4,8,10,11-penta-acetate.
• The crystal structure was solved and refined to determine atomic coordinates and bonding.

Main Results:

• X-ray analysis definitively confirmed the molecular structure of bergenin 3,4,8,10,11-penta-acetate.
• The experimental data aligns with and validates prior proposed structural assignments.

Conclusions:

• The structural assignment of bergenin 3,4,8,10,11-penta-acetate is unequivocally confirmed.
• This validation supports future studies on bergenin derivatives and their applications.