Pilomatricomas in Turner syndrome
Simon Wood1, Dai Nguyen, Kim Hutton
1Department of Burns and Plastic Surgery, Morriston Hospital, Swansea, UK. siwood@doctors.org.uk
Pediatric Dermatology
|September 16, 2008
Summary
Pilomatricomas, benign skin tumors, are uncommonly associated with Turner syndrome. This case report suggests a potential predisposition in girls with Turner syndrome, warranting clinical awareness.
Area of Science:
- Dermatology
- Genetics
- Pediatrics
Background:
- Pilomatricomas are benign cutaneous tumors originating from hair matrix cells, typically occurring in children.
- While often isolated, pilomatricomas have been linked to various inherited conditions.
- Turner syndrome is a genetic condition affecting females, characterized by chromosomal abnormalities.
Observation:
- A 10-year-old girl with Turner syndrome presented with two pilomatricomas, one of which was unusually large.
- This observation adds to a previous report of pilomatricoma in two patients with Turner syndrome.
Findings:
- The findings suggest a potential, albeit uncommon, association between pilomatricomas and Turner syndrome.
- This association may stem from the hair-bearing skin abnormalities frequently observed in Turner syndrome.
Implications:
- Clinicians managing pediatric cutaneous masses should consider this association.
- Increased awareness may aid in the early diagnosis and management of pilomatricomas in patients with Turner syndrome.
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