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Pilomatricomas in Turner syndrome

Simon Wood1, Dai Nguyen, Kim Hutton

  • 1Department of Burns and Plastic Surgery, Morriston Hospital, Swansea, UK. siwood@doctors.org.uk

Pediatric Dermatology
|September 16, 2008
PubMed

Insights

Pilomatricomas, benign skin tumors, are uncommonly associated with Turner syndrome. This case report suggests a potential predisposition in girls with Turner syndrome, warranting clinical awareness.

Area of Science:

  • Dermatology
  • Genetics
  • Pediatrics

Background:

  • Pilomatricomas are benign cutaneous tumors originating from hair matrix cells, typically occurring in children.
  • While often isolated, pilomatricomas have been linked to various inherited conditions.
  • Turner syndrome is a genetic condition affecting females, characterized by chromosomal abnormalities.

Observation:

  • A 10-year-old girl with Turner syndrome presented with two pilomatricomas, one of which was unusually large.
  • This observation adds to a previous report of pilomatricoma in two patients with Turner syndrome.

Findings:

  • The findings suggest a potential, albeit uncommon, association between pilomatricomas and Turner syndrome.
  • This association may stem from the hair-bearing skin abnormalities frequently observed in Turner syndrome.

Implications:

  • Clinicians managing pediatric cutaneous masses should consider this association.
  • Increased awareness may aid in the early diagnosis and management of pilomatricomas in patients with Turner syndrome.

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